MEDΦ / Team / Sebastian Kraszewski
Sebastian Kraszewski
dr hab. inż. · prof. PWr

Sebastian Kraszewski

Group leader · Associate Professor

Computational biophysics, drug design and AI in medicine.

About

Sebastian Kraszewski leads the MEDΦ Laboratory at the Department of Biomedical Engineering. He earned his PhD in 2010 at the Université de Franche-Comté in Besançon, working on the computational biophysics of carbon-nanotube interactions with biological membranes, and his habilitation in 2020 at the Silesian University of Technology on numerical methods in biomedical engineering.

His research connects atomistic simulation, membrane and transporter pharmacology, antimicrobial design and AI-assisted biomedical engineering. He has led the OPUS grant INNOSEPT on broad-spectrum antiseptics and the Foundation for Polish Science Homing Plus project GLU-TAT, and his work is indexed in Web of Science and Scopus with more than 1000 citations.

Beyond the lab he is Scientific Director of NCNI in Wrocław, co-founder of the Polish Society for the Treatment of Insulin Resistance, and a member of the Working Group on Artificial Intelligence at the Ministry of Digital Affairs, chairing its Health Section since 2026.

Research interests

molecular dynamicscomputational biophysicsdrug designAI in medicinemembrane transportersneurotechnologies

Selected publications

Kaijage N., Kraszewski S.P. Molecular mechanisms and computational insights into human SGLTs: advancing toward selective SGLT1 inhibition. Frontiers in Molecular Biosciences 2025; 12.

doi: 10.3389/fmolb.2025.1668400

Dyńka D., Rodzeń Ł., Rodzeń M. et al., Kraszewski S.P. et al. Intermittent fasting in the treatment of type 2 diabetes. Frontiers in Nutrition 2025; 12: 1629154.

Dyńka D., Rodzeń Ł., Rodzeń M., Kraszewski S.P. et al. Beneficial effects of the ketogenic diet on NAFLD/MAFLD. Journal of Clinical Medicine 2024; 13(16): 4857.

Rzycki M., Gładysiewicz-Kudrawiec M., Kraszewski S.P. Molecular guidelines for promising antimicrobial agents. Scientific Reports 2024; 14: 4641.

Bogusławska D.M., Kraszewski S.P. et al. Novel variant of the SLC4A1 gene associated with hereditary spherocytosis. Biomedicines 2023; 11(3): 784.

Rzycki M., Drabik D., Szostak-Paluch K., Hanus-Lorenz B.E., Kraszewski S.P. Unraveling the mechanism of octenidine and chlorhexidine on membranes. Biophysical Journal 2021; 120(16): 3392-3408.

doi: 10.1016/j.bpj.2021.06.027